Chemistry in daily life - tea

Tea is, like coffee, aromatic beverage and the most popular drinks in the world, which is commonly prepared by pouring hot or boiling water over cured leaves of the Camellia sinensis, an evergreen shrub native to Asia. But tea, possibly as a medicinal drink originated in China, has been consumed for thousands of years due for its elegant flavours and health benefits, in which polyphenols, flavonoids and phenolic acids, are of highly abundance and contribute a lot to its pleasant flavour and health prosperities.

Generally, tea is divided into at least six different types based on how it is processed, which are white tea (wilted and un-oxidized), yellow tea (un-wilted and un-oxidized, but allowed to yellow), green tea (un-wilted and un-oxidized), oolong tea (wilted, bruised, and partially oxidized), black tea (Chinese red tea, wilted, sometimes crushed, and fully oxidized,) and post-fermented tea (Chines black tea). But the most common ones are white, green, oolong, black and post-fermented tea.
 
Due to un-oxidized, green tea, for example, reportedly contains the highest concentration of powerful antioxidants called polyphenols, substances that fight free radicals (reactive oxygen species, ROS), which damage compounds in the body that change cells, damage DNA, and even cause cell death. There are several polyphenols in green tea, including epicatechin (EC), 2epicatechin-3-gallate (ECG),  epigallocatechin (EGC), epigallocatechin-3-gallate (EGCG),  catechin, and gallocatechin (GC), in which  EGCG is the most abundant, accounts for 65% of the total polyphenolic  content.
 
Those polyphenols have a number of health benefits and medical valuations.  High polyphenol components in green tea are reportedly believed more effective antioxidants than Vitamins C and E and to contribute to the aging process and development of a number of health problems, including cancer and heart disease. Chinese people traditionally used green tea as to help body to rid of excess fluid and  to improve body conditions, including regulating body temperature  and blood sugar, promoting digestion, and improving mental processes.

Clinical studies have suggested that antioxidant properties of green tea may help prevent atherosclerosis, particularly coronary artery disease, green tea lowers total cholesterol and raises HDL ("good") cholesterol in both animals and people and green tea may help protect against cancers, in which polyphenols is assumed to help kill cancerous cells and stop them from growing.
Many clinical studies suggest that the polyphenols in tea, especially green tea, may play an important role in the prevention of cancers, including bladder cancer, breast cancer, ovarian cancer, colorectal cancer, esophageal cancer, lung cancer, pancreatic cancer, prostate cancer, skin cancer and  stomach cancer.
 
Green tea has also been reportedly suggested  to help reduce inflammation, help prevent the development of type 1 diabetes and slow the progression once it has developed, to protect the liver from the damaging effects of toxic substances such as alcohol, help treat viral hepatitis, an inflammation of the liver, help to boost metabolism and help burn fat - combination of catechins (one of the polyphenols ) and caffeine to help body weight loss.

In addition, the metal-chelating properties of polyphenols (e.g., EGCG) are also important contributors to their protective effects (such as the iron-chelating properties of EGCG)  in neurodegenerative diseases , such as Parkinson's disease due to misregulated iron metabolism. Furthermore, polyphenols (e.g., catechin) have been reported to effects on several cellular and molecular targets in signal transduction pathways associated with cell death and cell survival (neuronal cells and in tumour epithelial/endothelial cells).

Molecular structure of EGCG.
Structural formula of epigallocatechin gallate

Molecular structure of catachin, one of flavanols in green tea.